"The Dominion had endured for over two thousand years, and will continue to endure, long after the Federation has crumbled to dust."
Weyoun 4

The Dominion is a major galactic power in the Milky Way galaxy that controls a large portion of the Gamma Quadrant. It was founded between 10,000 BC and 2,000 BC by the Changelings and is now populated by them and their genetically-engineered slave races.

Excaping persecution, the Changelings decided that if they were to live peacefully with the other beings of the galaxy, whom they called "solids", they decided they would have to dominated them. Finding a new homeworld in the Omarion Nebula, the Changelings renamed themselves the Founders and created the Vorta and the Jem'Hadar.(Star Trek)

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